A new meta-analysis in JAMA Neurology serves as a reminder that prompt treatment remains crucial for achieving successful reperfusion.
Each hour that passed from a patient’s arrival at a stroke EVT center to groin puncture reduced by 22 percent the odds of successful reperfusion, defined as a modified thrombolysis in cerebral infarction (mTICI) score of 2b or 3 after thrombectomy. Likewise, each hour from first imaging to groin puncture was linked to 26 percent lower odds of successful reperfusion.
The analysis included patient-level data from 728 participants in the EVT arms of randomized trials conducted by the HERMES (Highly Effective Reperfusion Using Multiple Endovascular Devices) group.
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