Among adults undergoing kidney transplantation, frailty was associated with cognitive decline over several years. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN) suggest that efforts are needed to preserve cognitive function in frail kidney transplant recipients.
Lower kidney function is associated with worse cognitive function, but cognitive impairment is still present in many kidney transplant recipients after their kidney function is restored. Also, frailty—a decline in reserve and function across multiple physiologic systems that can cause physical and cognitive impairments— is a predictor of adverse outcomes in kidney transplant populations. It is unclear whether frail recipients experience post-transplant cognitive improvements.
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American Society of Nephrology leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.
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